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NPR's Robert Siegel speaks with political consultant Doug Cole, of High Ground, about how Sen. Flake's announcement is dramatically changing the political landscape in Arizona. He says it's having a cascading effect as Arizona lawmakers, who would never consider running against Flake, weigh getting into the primary race.

U.S. troops are on the ground in Syria training local forces to fight ISIS. But Turkish troops and their local allies are on verge of a confrontation with them.

Elections in Virginia this fall are the first big test for state-level Democrats in the Trump era and whether they can use the president's unpopularity to gain ground in the state legislature.

NPR's Ari Shapiro speaks with San Francisco-based billionaire Tom Steyer about why he's given millions of his own money to back progressive candidates and to put pressure on impeaching the president.

Vice President Kamala Harris visited the southern U.S. border on Friday. NPR's Rachel Martin talks to Republican Rep. Tony Gonzalez of Texas about the trip and the criticism against Harris.

The South American soccer federation, which is part of FIFA, has diplomatic status on par with an embassy. That means that inside its luxurious grounds, Paraguayan law does not apply.

The campaign to label foods containing genetically modified organisms is gaining ground in some parts of the U.S. But GMO ingredients are found in some 70 percent of foods we buy in the U.S. Would a ubiquitous GMO label scare off consumers, or would they learn to accept it and buy anyway?

Now that U.S. forces are set to leave for good, what is next for Afghanistan? NPR's Mary Louise Kelly talks with Patricia Gossman, Associate Asia Director for Human Rights Watch.

Images of Ukraine are flooding social media, but experts warn they don't show the full picture and can sometimes give a misleading account of the conflict on the ground.

Actor Leonardo DiCaprio, who stars as a high-living stock swindler in The Wolf of Wall Street, tells NPR's David Greene that it was "incredibly freeing" to play a character with no moral high ground.