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The Biden administration scrambles to respond as new data from the Centers for Disease Control and Prevention show overdose deaths surged to more than 100,000 fatalities.

The man who leads the criminal division at the Justice Department has a powerful personal story: one of his brothers died in gun violence and another is a police officer.

The airstrike follows a deadly week of attacks that have intensified nearly a year of fighting between Israel and the Iran-backed Lebanese militia Hezbollah.

As President Vladimir Putin approaches his 20th year in power, anger over bread-and-butter issues is sparking demonstrations across the country.

The Defense Secretary faced scrutiny on two fronts Thursday: over a strike that killed survivors on an alleged drug boat in the Caribbean and his use of Signal to discuss U.S. attack plans on Yemen.

After delays, Rupert Murdoch will be deposed in a defamation lawsuit brought by Dominion Voting Systems, which also alleges that Fox News destroyed messages from star Sean Hannity and others.

The 65-team NCAA men's basketball tournament begins this week. Defending champion Florida, North Carolina, Ohio State, and Kansas are the top seeds. In picking this year's at-large teams, the selection committee favored clubs from the power conferences.

Iran asked Interpol to arrest President Trump and dozens of other American officials for the 2020 assassination of Gen. Qassem Soleimani.

Andrew Weissmann, one of the best-known lawyers in special counsel Robert Mueller's office, is set to depart soon from that job and the Justice Department, NPR has learned.

The 10-day-old government shut down and the need to raise the federal debt limit next week have been tied together as a single political crisis. But now, House Republicans seem ready to cleave the debt ceiling debate. Economists of all stripes say breaching the debt ceiling could be catastrophic, and on Thursday, House Speaker John Boehner said he is prepared to support a bill to raise the debt ceiling for six weeks if the president will agree to negotiations on long-term deficit reduction. None of this has anything to do with the initial fight to repeal or delay the Affordable Care Act, but may be a start toward resolution.